Cities Building Community Wealth

As cities struggle with rising inequality, widespread economic hardship, and racial disparities, something surprising and hopeful is also stirring. In a growing number of America's cities, a more inclusive, community-based approach to economic development is being taken up by a new breed of economic development professionals and mayors. This approach to economic development could be on the cusp of going to scale. It's time it had a name. We call it community wealth building

Raising Student Voices: Student Action for University Community Investment

This new report from The Democracy Collaborative and the Responsible Endowments Coalition seeks to connect struggling communities to local institutional wealth through engaging student activism. The report profiles three administration-led initiatives and three student-led initiatives, as well as five potential future partnerships, where institutional investments are directed into local communities in a way that empowers low-income residents, develops small businesses, and generates sustainable economic development

Chronology: MSFC Space Station program, 1982 - present. Major events

The Marshall Space Flight Center (MSFC) maintains an active program to capture historical information and documentation on the MSFC's roles regarding Space Shuttle and Space Station. Marshall History Report 12, called Chronology: MSFC Space Station Program, 1982-Present, is presented. It contains synopses of major events listed according to the dates of their occurrence. Indices follow the synopses and provide additional data concerning the events listed. The Event Index provides a brief listing of all the events without synopses. The Element Index lists the specific elements of the Space Station Program under consideration in the events. The Location Index lists the locations where the events took place. The indices and synopses may be cross-referenced by using dates

Effects of Dietary Fish-oil Supplement and Acute Eccentric Exercise on Inflammatory Markers during Different Phases of Menstrual Cycle

Fish-oil supplementation may play a positive role in inflammation. Matrix Metalloproteinases (MMPs) are important in controlling tumor growth, metastasis, angiogenesis, and inflammation. Several tissue inhibitors of MMPs (TIMPs) are known to regulate the activity of specific MMPs. PURPOSE: To examine the effects of dietary fish-oil supplementation and acute eccentric exercise on MMP-1, -2, -9, and -10 and TIMP-1, -2, -3, and -4 during two different phases of menstrual cycle. METHODS: As a randomized, double-blind, and placebo-controlled design, 22 college-aged women (age= 20.86 ± 1.39 years) were randomly assigned to either a fish oil (FOG, N=11) or a placebo group (PG, N=11). Participants in the FOG ingested 6 capsules of fish oil per day (total 6.0g, containing 2.4g eicosapentaenoic acid and 1.8g docosahexaenoic acid), while the PG took 6 capsules of safflower oil per day for 3 weeks. Participants in each group performed an acute bout of eccentric single-leg exercise (10 sets of 10 repetitions with a 3-min rest between sets at an isokinetic speed of 30⁰/second) during the mid-follicular (MF) and mid-luteal (ML) phases. The leg exercised for the MF phase was randomly selected and the opposing leg exercised during the ML phase. Overnight blood samples were collected at baseline, 6-hr post-exercise (6hr-PE), and 24-hr PE during the MF and ML phases. Data were analyzed by a separate 2 x 2 x 3 ANOVA with repeated measures along with an appropriate post-hoc test for any significant interactions (p \u3c 0.05). RESULTS: A significant interaction effect (p=0.005) in MMP-1 indicated that MMP-1 in the FOG (193.71±21.72 pg/mL) was higher than that of the placebo group (120.79±21.72 pg/mL) during the MF phase. Both TIMP-1 and -3 were significantly higher (p=.043 and p=.037, respectively) in the FOG (68674.71±2238.56 and 3827.12±193.67 pg/mL, respectively) than the placebo group (62119.26±2178.86 and 3238.94±186.73 pg/mL, respectively). CONCLUSION: Acute eccentric exercise did not affect MMPs and TIMPs in healthy, young females. MMP-1 was the only proteinase affected by the menstrual cycle and a decrease in MMP-1 during the ML phase might be related to elevated estradiol levels. Elevated TIMP-1 and -3 following the 3-weeks of fish-oil supplementation suggested a potential anti-inflammatory effect of the fish-oil supplementation by inhibiting activation of MMPs. It is recommended that an extended period of fish oil supplementation be implemented to further examine its anti-inflammatory effect on other inflammatory biomarkers in different sample groups including both pre- and post-menopausal women

How well do UK assistantships equip medical students for graduate practice? Think EPAs

The goal of better medical student preparation for clinical practice drives curricular initiatives worldwide. Learning theory underpins Entrustable Professional Activities (EPAs) as a means of safe transition to independent practice. Regulators mandate senior assistantships to improve practice readiness. It is important to know whether meaningful EPAs occur in assistantships, and with what impact. Final year students at one UK medical school kept learning logs and audio-diaries for six one-week periods during a year-long assistantship. Further data were also obtained through interviewing participants when students and after three months as junior doctors. This was combined with data from new doctors from 17 other UK schools. Realist methods explored what worked for whom and why. 32 medical students and 70 junior doctors participated. All assistantship students reported engaging with EPAs but gaps in the types of EPAs undertaken exist, with level of entrustment and frequency of access depending on the context. Engagement is enhanced by integration into the team and shared understanding of what constitutes legitimate activities. Improving the shared understanding between student and supervisor of what constitutes important assistantship activity may result in an increase in the amount and/or quality of EPAs achieved

The demography of free-roaming dog populations and applications to disease and population control

Understanding the demography of domestic dog populations is essential for effective disease control, particularly of canine-mediated rabies. Demographic data are also needed to plan effective population management. However, no study has comprehensively evaluated the contribution of demographic processes (i.e. births, deaths and movement) to variations in dog population size or density, or determined the factors that regulate these processes, including human factors. We report the results of a 3-year cohort study of domestic dogs, which is the first to generate detailed data on the temporal variation of these demographic characteristics. The study was undertaken in two communities in each of Bali, Indonesia and Johannesburg, South Africa, in rabies-endemic areas and where the majority of dogs were free-roaming. None of the four communities had been engaged in any dog population management interventions by local authorities or animal welfare organizations. All identified dogs in the four communities were monitored individually throughout the study. We observed either no population growth or a progressive decline in population size during the study period. There was no clear evidence that population size was regulated through environmental resource constraints. Rather, almost all of the identified dogs were owned and fed regularly by their owners, consistent with population size regulated by human demand. Finally, a substantial fraction of the dogs originated from outside the population, entirely through the translocation of dogs by people, rather than from local births. These findings demonstrate that previously reported growth of dog populations is not a general phenomenon and challenge the widely held view that free-roaming dogs are unowned and form closed populations. Synthesis and applications. These observations have broad implications for disease and population control. The accessibility of dogs for vaccination and evaluation through owners and the movement of dogs (some of them infected) by people will determine the viable options for disease control strategies. The impact of human factors on population dynamics will also influence the feasibility of annual vaccination campaigns to control rabies and population control through culling or sterilization. The complex relationship between dogs and people is critically important in the transmission and control of canine-mediated rabies. For effective management, human factors must be considered in the development of disease and population control programmes

Effects of Dehydration on Resistance Training: An Ongoing Study

Introduction: Dehydration via hot bath has been shown to impair resistance training performance when performed the same day. The performance decrements in this instance could potentially be due to a combination of the dehydration and residual effects of the heat exposure and not of the dehydration alone. To date, no research has examined the effects of previous night dehydration on resistance training performance. Purpose: The purpose of this ongoing study was to determine the effects of previous night dehydration on performance and perceptual measures during a full-body resistance training protocol. Methods: Healthy, resistance trained males (n = 4) completed two bouts of a full body resistance training protocol (three sets to failure for bench press, lat pull, overhead press, bicep curl, triceps push down, and leg press), dehydrated (~3% body weight) (DT), or heat exposed with fluid replacement (HT). Heart rate (HR) was taken after every set, and participants estimated ratings of perceived exertion (RPE) after each exercise. Session RPE (SRPE) was estimated 5 minutes following completion of the protocol and estimations for feelings of recovery (PRS), perceived readiness to exercise (PR), thirst, and sleep quality. Results: Analysis revealed a significantly less (p = \u3c 0.001) total reps were completed for DT (163.0 ± 4.8) compared to HT (191.3 ± 10.3), though no differences were found for reps per exercise. No significant differences were found for HR (DT vs HT) at any time point. RPE was significantly higher for DT following bicep curl (p = 0.03) (DT: 7.8 ± 0.96, HT: 6.0 ± 0.82) and triceps push down (p = 0.03) (DT: 7.5 ± 0.58, HT: 6.0 ± 0.82). SRPE was significantly higher (p = 0.003) for DT (8.0 ± 0.0) vs HT (6.3 ± 0.5). Significant differences for PRS (p = 0.004) (DT: 5.0 ± 1.4, HT: 7.5 ± 0.58) and PR (p = \u3c 0.001) (DT: 5.0 ± 0.0, HT: 2.5 ± 0.58) indicate participants expected impaired performance during DT. Feelings of thirst were significantly higher (p = 0.001) for DT (7.98 ± 0.94) vs HT (2.73 ± 1.11). No differences were found for estimations of sleep quality (p = 0.59). Conclusion: Even though only preliminary data from a study presently ongoing, the present results suggest that previous night dehydration has a negative influence on both performance and perceptual measures

Omega-3 Supplementation, Menstrual Cycle, and Acute Eccentric Exercise on Plasma Lipid Profiles

Omega-3 fatty acids supplementation and the menstrual cycle may independently influence plasma lipids and lipoproteins following acute exercise. PURPOSE: The current study investigated the effects of dietary fish oil supplement and acute eccentric exercise on plasma lipids and lipoproteins during two different phases of the menstrual cycle [mid-follicular (MF) vs. mid-luteal phase (ML)]. METHODS: As a double-blind, placebo-controlled design, 22 healthy young females (age= 20.86±1.39 years) volunteered. Participants were randomly assigned to either the fish oil (N=11) or the placebo (N=11) group. The fish oil group took a total of 6 capsules of fish oil per day (6g total; each capsule with 2.4 g of eicosapentaenoic acid and 1.8 g of docosahexaenoic acid), while the placebo group took 6 capsules of safflower oil/day (6g total; 2.8 g of lauric acid, 1.1g of myristic acid, 0.4 g of caprylic acid, 0.4 g of oleic acid, and 0.09 mg of linoleic acid) for 3 weeks. Participants in each group performed an acute eccentric single-leg exercise protocol during the MF and ML phases, which consisted of 10 sets of 10 repetitions with a 3-min resting between sets at an isokinetic speed of 30⁰/sec. The leg exercised for the MF phase was randomly selected and the opposing leg exercised during the ML phase. Plasma samples were collected at pre-, 6-hours post-exercise (6-hr PE), and 24-hours post-exercise (24-hr PE)] to analyze total cholesterol (TC), high-density lipoprotein (HDL-C), lipoprotein (a), very low-density lipoprotein (VLDL-C), and low-density lipoprotein (LDL-C). Data were analyzed using a multivariate analysis of variance (p \u3c 0.05). If a significant interaction was found, a Tukey’s post-hoc test was performed. RESULTS: Plasma lipids and lipoproteins were not different between the fish oil and placebo groups or before and after the acute eccentric leg exercise. However, HDL-C was significantly higher (p = 0.041) during the ML (61.66 ± 2.44 mg/dL) phase than that of the MF (54.53 ± 2.44 mg/dL) phase. CONCLUSION: Although it didn’t reach a statistical significance, the overall lipid and lipoprotein profile tended to improve following a relatively short-term fish oil supplement in healthy, young women. Acute eccentric exercise may not negatively affect plasma lipids and lipoproteins. Elevated HDL-C during the mid-luteal phase may possibly be associated with increased estradiol levels. It is recommended for future studies that an extended period of fish oil supplement using different dosages and exercise regimen be implemented to examine a long-term benefit of fish oil supplement in a variety of sample groups

In Solidarity

This edition of Next Page is a departure from our usual question and answer format with a featured campus reader. Instead, we asked speakers who participated in the College’s recent Student Solidarity Rally (March 1, 2017) to recommend readings that might further our understanding of the topics on which they spoke